Publikationer

2018

  • Abe C, Rahman Q, Langstrom N, Ryden E, Ingvar M, Landen M. Cortical brain structure and sexual orientation in adult females with bipolar disorder or attention deficit hyperactivity disorder. Brain Behav. 2018;8(7):e00998.
  • Abe C, Rolstad S, Petrovic P, Ekman CJ, Sparding T, Ingvar M, et al. Bipolar disorder type I and II show distinct relationships between cortical thickness and executive function. Acta Psychiatr Scand. 2018.
  • Chang H, Hoshina N, Zhang C, Ma Y, Cao H, Wang Y, et al. The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders. Mol Psychiatry. 2018;23(2):400-12.
  • Chen CY, Lee PH, Castro VM, Minnier J, Charney AW, Stahl EA, et al. Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records. Transl Psychiatry. 2018;8(1):86.
  • Hansson C, Joas E, Palsson E, Hawton K, Runeson B, Landen M. Risk factors for suicide in bipolar disorder: a cohort study of 12 850 patients. Acta Psychiatr Scand. 2018.
  • Hibar DP, Westlye LT, Doan NT, Jahanshad N, Cheung JW, Ching CRK, et al. Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Mol Psychiatry. 2018;23(4):932-42.
  • International Consortium on Lithium G, Amare AT, Schubert KO, Hou L, Clark SR, Papiol S, et al. Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. JAMA Psychiatry. 2018;75(1):65-74.
  • Kalman JL, Papiol S, Forstner AJ, Heilbronner U, Degenhardt F, Strohmaier J, et al. Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study. Bipolar Disord. 2018.
  • Landen M, Song J. More Efforts Needed to Clarify the Effect of Lithium in Bipolar Disorder: Response to Terao et al. Am J Psychiatry. 2018;175(1):80-1.
  • Meehan AD, Udumyan R, Kardell M, Landen M, Jarhult J, Wallin G. Lithium-Associated Hypercalcemia: Pathophysiology, Prevalence, Management. World J Surg. 2018;42(2):415-24.
  • Popiolek K, Brus O, Elvin T, Landen M, Lundberg J, Nordanskog P, et al. Rehospitalization and suicide following electroconvulsive therapy for bipolar depression-A population-based register study. J Affect Disord. 2018;226:146-54.
  • Rangan AV, McGrouther CC, Kelsoe J, Schork N, Stahl E, Zhu Q, et al. A loop-counting method for covariate-corrected low-rank biclustering of gene-expression and genome-wide association study data. PLoS Comput Biol. 2018;14(5):e1006105.
  • Reinbold CS, Forstner AJ, Hecker J, Fullerton JM, Hoffmann P, Hou L, et al. Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder. Front Psychiatry. 2018;9:207.
  • Rundgren S, Brus O, Bave U, Landen M, Lundberg J, Nordanskog P, et al. Improvement of postpartum depression and psychosis after electroconvulsive therapy: A population-based study with a matched comparison group. J Affect Disord. 2018;235:258-64.

 

2017

  • Bauer M, Glenn T, Alda M, Aleksandrovich MA, Andreassen OA, Angelopoulos E, et al. Solar insolation in springtime influences age of onset of bipolar I disorder. Acta Psychiatr Scand. 2017;136(6):571-82.
  • Brus O, Cao Y, Gustafsson E, Hulten M, Landen M, Lundberg J, et al. Self-assessed remission rates after electroconvulsive therapy of depressive disorders. Eur Psychiatry. 2017;45:154-60.
  • Brus O, Nordanskog P, Bave U, Cao Y, Hammar A, Landen M, et al. Subjective Memory Immediately Following Electroconvulsive Therapy. J ECT. 2017;33(2):96-103.
  • Cesta CE, Kuja-Halkola R, Lehto K, Iliadou AN, Landen M. Polycystic ovary syndrome, personality, and depression: A twin study. Psychoneuroendocrinology. 2017;85:63-8.
  • Chang H, Li L, Peng T, Grigoroiu-Serbanescu M, Bergen SE, Landen M, et al. Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1. Mol Neurobiol. 2017;54(7):5166-76.
  • Charney AW, Ruderfer DM, Stahl EA, Moran JL, Chambert K, Belliveau RA, et al. Evidence for genetic heterogeneity between clinical subtypes of bipolar disorder. Transl Psychiatry. 2017;7(1):e993.
  • Cremaschi L, Kardell M, Johansson V, Isgren A, Sellgren CM, Altamura AC, et al. Prevalences of autoimmune diseases in schizophrenia, bipolar I and II disorder, and controls. Psychiatry Res. 2017;258:9-14.
  • Ekman CJ, Petrovic P, Johansson AG, Sellgren C, Ingvar M, Landen M. A History of Psychosis in Bipolar Disorder is Associated With Gray Matter Volume Reduction. Schizophr Bull. 2017;43(1):99-107.
  • Holm J, Brus O, Bave U, Landen M, Lundberg J, Nordanskog P, et al. Improvement of cycloid psychosis following electroconvulsive therapy. Nord J Psychiatry. 2017;71(6):405-10.
  • Isgren A, Sellgren C, Ekman CJ, Holmen-Larsson J, Blennow K, Zetterberg H, et al. Markers of neuroinflammation and neuronal injury in bipolar disorder: Relation to prospective clinical outcomes. Brain Behav Immun. 2017;65:195-201.
  • Javaras KN, Rickert ME, Thornton LM, Peat CM, Baker JH, Birgegard A, et al. Paternal age at childbirth and eating disorders in offspring. Psychol Med. 2017;47(3):576-84.
  • Joas E, Karanti A, Song J, Goodwin GM, Lichtenstein P, Landen M. Pharmacological treatment and risk of psychiatric hospital admission in bipolar disorder. Br J Psychiatry. 2017;210(3):197-202.
  • Johansson V, Jakobsson J, Fortgang RG, Zetterberg H, Blennow K, Cannon TD, et al. Cerebrospinal fluid microglia and neurodegenerative markers in twins concordant and discordant for psychotic disorders. Eur Arch Psychiatry Clin Neurosci. 2017;267(5):391-402.
  • Kegel ME, Johansson V, Wetterberg L, Bhat M, Schwieler L, Cannon TD, et al. Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity. Psychiatry Res. 2017;247:105-12.
  • Landen M, Viktorin A. Calling for More Research of Medication Effects in Bipolar Disorder: Response to Ketter and Dell’Osso. Am J Psychiatry. 2017;174(8):804-5.
  • Lautner R, Insel PS, Skillback T, Olsson B, Landen M, Frisoni GB, et al. Preclinical effects of APOE epsilon4 on cerebrospinal fluid Abeta42 concentrations. Alzheimers Res Ther. 2017;9(1):87.
  • Najar H, Joas E, Kardell M, Palsson E, Landen M. Weight gain with add-on second-generation antipsychotics in bipolar disorder: a naturalistic study. Acta Psychiatr Scand. 2017;135(6):606-11.
  • Palsson E, Sellgren C, Ryden E, Kizza R, Pelanis A, Zetterberg H, et al. Cerebrospinal fluid monoamine metabolite profiles in bipolar disorder, ADHD, and controls. J Neural Transm (Vienna). 2017;124(9):1135-43.
  • Power RA, Tansey KE, Buttenschon HN, Cohen-Woods S, Bigdeli T, Hall LS, et al. Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Biol Psychiatry. 2017;81(4):325-35.
  • Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, et al. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry. 2017;22(8):1223.
  • Song J, Kuja-Halkola R, Sjolander A, Bergen SE, Larsson H, Landen M, et al. Specificity in Etiology of Subtypes of Bipolar Disorder: Evidence From a Swedish Population-Based Family Study. Biol Psychiatry. 2017.
  • Song J, Sjolander A, Joas E, Bergen SE, Runeson B, Larsson H, et al. Suicidal Behavior During Lithium and Valproate Treatment: A Within-Individual 8-Year Prospective Study of 50,000 Patients With Bipolar Disorder. Am J Psychiatry. 2017;174(8):795-802.
  • Sparding T, Palsson E, Joas E, Hansen S, Landen M. Personality traits in bipolar disorder and influence on outcome. BMC Psychiatry. 2017;17(1):159.
  • Sparding T, Silander K, Palsson E, Ostlind J, Ekman CJ, Sellgren CM, et al. Classification of cognitive performance in bipolar disorder. Cogn Neuropsychiatry. 2017;22(5):407-21.
  • van Hulzen KJE, Scholz CJ, Franke B, Ripke S, Klein M, McQuillin A, et al. Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. Biol Psychiatry. 2017;82(9):634-41.
  • Viktorin A, Ryden E, Thase ME, Chang Z, Lundholm C, D’Onofrio BM, et al. The Risk of Treatment-Emergent Mania With Methylphenidate in Bipolar Disorder. Am J Psychiatry. 2017;174(4):341-8.
  • Witt SH, Streit F, Jungkunz M, Frank J, Awasthi S, Reinbold CS, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry. 2017;7(6):e1155.

 

2016

  • Abe C, Ekman CJ, Sellgren C, Petrovic P, Ingvar M, Landen M. Cortical thickness, volume and surface area in patients with bipolar disorder types I and II. J Psychiatry Neurosci. 2016;41(4):240-50.
  • Brundin L, Sellgren CM, Lim CK, Grit J, Palsson E, Landen M, et al. An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. Transl Psychiatry. 2016;6(8):e865.
  • Cesta CE, Mansson M, Palm C, Lichtenstein P, Iliadou AN, Landen M. Polycystic ovary syndrome and psychiatric disorders: Co-morbidity and heritability in a nationwide Swedish cohort. Psychoneuroendocrinology. 2016;73:196-203.
  • Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, et al. Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med. 2016;46(8):1613-23.
  • Genovese G, Fromer M, Stahl EA, Ruderfer DM, Chambert K, Landen M, et al. Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia. Nat Neurosci. 2016;19(11):1433-41.
  • Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, et al. Exome Sequencing of Familial Bipolar Disorder. JAMA Psychiatry. 2016;73(6):590-7.
  • Hennessy TW, Bruden D, Castrodale L, Komatsu K, Erhart LM, Thompson D, et al. A case-control study of risk factors for death from 2009 pandemic influenza A(H1N1): is American Indian racial status an independent risk factor? Epidemiol Infect. 2016;144(2):315-24.
  • Hibar DP, Westlye LT, van Erp TG, Rasmussen J, Leonardo CD, Faskowitz J, et al. Subcortical volumetric abnormalities in bipolar disorder. Mol Psychiatry. 2016;21(12):1710-6.
  • Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet. 2016;25(15):3383-94.
  • Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet. 2016;387(10023):1085-93.
  • Hughes T, Hansson L, Sonderby IE, Athanasiu L, Zuber V, Tesli M, et al. A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia. Biol Psychiatry. 2016;80(4):323-30.
  • Jakobsson J, Palsson E, Sellgren C, Rydberg F, Ekman A, Zetterberg H, et al. CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder. Br J Psychiatry. 2016;208(2):195-6.
  • Karanti A, Kardell M, Lundberg U, Landen M. Changes in mood stabilizer prescription patterns in bipolar disorder. J Affect Disord. 2016;195:50-6.
  • Larsson I, Hulthen L, Landen M, Palsson E, Janson P, Stener-Victorin E. Dietary intake, resting energy expenditure, and eating behavior in women with and without polycystic ovary syndrome. Clin Nutr. 2016;35(1):213-8.
  • Li M, Huang L, Grigoroiu-Serbanescu M, Bergen SE, Landen M, Hultman CM, et al. Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. Mol Neurobiol. 2016;53(10):6608-19.
  • Li M, Luo XJ, Landen M, Bergen SE, Hultman CM, Li X, et al. Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. Br J Psychiatry. 2016;208(2):128-37.
  • Lundh A, Forsman M, Serlachius E, Langstrom N, Lichtenstein P, Landen M. Psychosocial functioning in adolescent patients assessed with Children’s Global Assessment Scale (CGAS) predicts negative outcomes from age 18: A cohort study. Psychiatry Res. 2016;242:295-301.
  • Nordenskjold A, Martensson B, Pettersson A, Heintz E, Landen M. Effects of Hesel-coil deep transcranial magnetic stimulation for depression – a systematic review. Nord J Psychiatry. 2016;70(7):492-7.
  • Petrovic P, Ekman CJ, Klahr J, Tigerstrom L, Ryden G, Johansson AG, et al. Significant grey matter changes in a region of the orbitofrontal cortex in healthy participants predicts emotional dysregulation. Soc Cogn Affect Neurosci. 2016;11(7):1041-9.
  • Rolstad S, Abe C, Olsson E, Eckerstrom C, Landen M. Cognitive reserve lessens the burden of white matter lesions on executive functions in bipolar disorder. Psychol Med. 2016;46(15):3095-104.
  • Rolstad S, Sellgren Majkowitz C, Joas E, Ekman CJ, Palsson E, Landen M. Polymorphisms of BDNF and CACNA1C are not associated with cognitive functioning in bipolar disorder or healthy controls. Cogn Neuropsychiatry. 2016;21(3):271-8.
  • Schwieler L, Samuelsson M, Frye MA, Bhat M, Schuppe-Koistinen I, Jungholm O, et al. Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients. J Neuroinflammation. 2016;13(1):51.
  • Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, et al. A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder. Mol Psychiatry. 2016;21(10):1342-50.
  • Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, et al. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry. 2016;21(9):1290-7.
  • Viktorin A, Lichtenstein P, Lundholm C, Almqvist C, D’Onofrio BM, Larsson H, et al. Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age. Int J Epidemiol. 2016;45(1):170-7.
  • Viktorin A, Meltzer-Brody S, Kuja-Halkola R, Sullivan PF, Landen M, Lichtenstein P, et al. Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression. Am J Psychiatry. 2016;173(2):158-65.
  • Yoshimi N, Futamura T, Bergen SE, Iwayama Y, Ishima T, Sellgren C, et al. Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis. Mol Psychiatry. 2016;21(11):1504-10.
  • Yoshimi N, Futamura T, Kakumoto K, Salehi AM, Sellgren CM, Holmen-Larsson J, et al. Blood metabolomics analysis identifies abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism in bipolar disorder. BBA Clin. 2016;5:151-8.
  • Abe C, Ekman CJ, Sellgren C, Petrovic P, Ingvar M, Landen M. Cortical thickness, volume and surface area in patients with bipolar disorder types I and II. J Psychiatry Neurosci. 2016;41(4):240-50.
  • Brundin L, Sellgren CM, Lim CK, Grit J, Palsson E, Landen M, et al. An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation. Transl Psychiatry. 2016;6(8):e865.
  • Cesta CE, Mansson M, Palm C, Lichtenstein P, Iliadou AN, Landen M. Polycystic ovary syndrome and psychiatric disorders: Co-morbidity and heritability in a nationwide Swedish cohort. Psychoneuroendocrinology. 2016;73:196-203.
  • Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, et al. Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med. 2016;46(8):1613-23.
  • Genovese G, Fromer M, Stahl EA, Ruderfer DM, Chambert K, Landen M, et al. Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia. Nat Neurosci. 2016;19(11):1433-41.
  • Goes FS, Pirooznia M, Parla JS, Kramer M, Ghiban E, Mavruk S, et al. Exome Sequencing of Familial Bipolar Disorder. JAMA Psychiatry. 2016;73(6):590-7.
  • Hennessy TW, Bruden D, Castrodale L, Komatsu K, Erhart LM, Thompson D, et al. A case-control study of risk factors for death from 2009 pandemic influenza A(H1N1): is American Indian racial status an independent risk factor? Epidemiol Infect. 2016;144(2):315-24.
  • Hibar DP, Westlye LT, van Erp TG, Rasmussen J, Leonardo CD, Faskowitz J, et al. Subcortical volumetric abnormalities in bipolar disorder. Mol Psychiatry. 2016;21(12):1710-6.
  • Hou L, Bergen SE, Akula N, Song J, Hultman CM, Landen M, et al. Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder. Hum Mol Genet. 2016;25(15):3383-94.
  • Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, et al. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. Lancet. 2016;387(10023):1085-93.
  • Hughes T, Hansson L, Sonderby IE, Athanasiu L, Zuber V, Tesli M, et al. A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia. Biol Psychiatry. 2016;80(4):323-30.
  • Jakobsson J, Palsson E, Sellgren C, Rydberg F, Ekman A, Zetterberg H, et al. CACNA1C polymorphism and altered phosphorylation of tau in bipolar disorder. Br J Psychiatry. 2016;208(2):195-6.
  • Karanti A, Kardell M, Lundberg U, Landen M. Changes in mood stabilizer prescription patterns in bipolar disorder. J Affect Disord. 2016;195:50-6.
  • Larsson I, Hulthen L, Landen M, Palsson E, Janson P, Stener-Victorin E. Dietary intake, resting energy expenditure, and eating behavior in women with and without polycystic ovary syndrome. Clin Nutr. 2016;35(1):213-8.
  • Li M, Huang L, Grigoroiu-Serbanescu M, Bergen SE, Landen M, Hultman CM, et al. Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. Mol Neurobiol. 2016;53(10):6608-19.
  • Li M, Luo XJ, Landen M, Bergen SE, Hultman CM, Li X, et al. Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. Br J Psychiatry. 2016;208(2):128-37.
  • Lundh A, Forsman M, Serlachius E, Langstrom N, Lichtenstein P, Landen M. Psychosocial functioning in adolescent patients assessed with Children’s Global Assessment Scale (CGAS) predicts negative outcomes from age 18: A cohort study. Psychiatry Res. 2016;242:295-301.
  • Nordenskjold A, Martensson B, Pettersson A, Heintz E, Landen M. Effects of Hesel-coil deep transcranial magnetic stimulation for depression – a systematic review. Nord J Psychiatry. 2016;70(7):492-7.
  • Petrovic P, Ekman CJ, Klahr J, Tigerstrom L, Ryden G, Johansson AG, et al. Significant grey matter changes in a region of the orbitofrontal cortex in healthy participants predicts emotional dysregulation. Soc Cogn Affect Neurosci. 2016;11(7):1041-9.
  • Rolstad S, Abe C, Olsson E, Eckerstrom C, Landen M. Cognitive reserve lessens the burden of white matter lesions on executive functions in bipolar disorder. Psychol Med. 2016;46(15):3095-104.
  • Rolstad S, Sellgren Majkowitz C, Joas E, Ekman CJ, Palsson E, Landen M. Polymorphisms of BDNF and CACNA1C are not associated with cognitive functioning in bipolar disorder or healthy controls. Cogn Neuropsychiatry. 2016;21(3):271-8.
  • Schwieler L, Samuelsson M, Frye MA, Bhat M, Schuppe-Koistinen I, Jungholm O, et al. Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients. J Neuroinflammation. 2016;13(1):51.
  • Sellgren CM, Kegel ME, Bergen SE, Ekman CJ, Olsson S, Larsson M, et al. A genome-wide association study of kynurenic acid in cerebrospinal fluid: implications for psychosis and cognitive impairment in bipolar disorder. Mol Psychiatry. 2016;21(10):1342-50.
  • Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, et al. Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Mol Psychiatry. 2016;21(9):1290-7.
  • Viktorin A, Lichtenstein P, Lundholm C, Almqvist C, D’Onofrio BM, Larsson H, et al. Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age. Int J Epidemiol. 2016;45(1):170-7.
  • Viktorin A, Meltzer-Brody S, Kuja-Halkola R, Sullivan PF, Landen M, Lichtenstein P, et al. Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression. Am J Psychiatry. 2016;173(2):158-65.
  • Yoshimi N, Futamura T, Bergen SE, Iwayama Y, Ishima T, Sellgren C, et al. Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis. Mol Psychiatry. 2016;21(11):1504-10.
  • Yoshimi N, Futamura T, Kakumoto K, Salehi AM, Sellgren CM, Holmen-Larsson J, et al. Blood metabolomics analysis identifies abnormalities in the citric acid cycle, urea cycle, and amino acid metabolism in bipolar disorder. BBA Clin. 2016;5:151-8.

 

2015

  • Polymorphisms of dopamine pathway genes NRG1 and LMX1A are associated with cognitive performance in bipolar disorder. Rolstad S, Pålsson E, Ekman CJ, Eriksson E, Sellgren C, Landén M. Bipolar Disord. 2015 Dec;17(8):859-68.
  • A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia. Hughes T, Hansson L, Sønderby IE, Athanasiu L, Zuber V, Tesli M, Song J, Hultman CM, Bergen SE, Landén M, Melle I, Andreassen OA, Djurovic S. Biol Psychiatry. 2015 Nov 11.
  • Genome-wide association study identifies SESTD1 as a novel risk gene for lithium-responsive bipolar disorder. Song J, Bergen SE, Di Florio A, Karlsson R, Charney A, Ruderfer DM, Stahl EA; Members of the International Cohort Collection for Bipolar Disorder (ICCBD), Chambert KD, Moran JL, Gordon-Smith K, Forty L, Green EK, Jones I, Jones L, Scolnick EM, Sklar P, Smoller JW, Lichtenstein P, Hultman C, Craddock N, Landén M, Smoller JW, Perlis RH, Lee PH, Castro VM, Hoffnagle AG, Sklar P, Stahl EA, Purcell SM, Ruderfer DM, Charney AW, Roussos P, Michele Pato CP, Medeiros H, Sobel J, Craddock N, Jones I, Forty L, Florio AD, Green E, Jones L, Gordon-Smith K, Landen M, Hultman C, Jureus A, Bergen S, McCarroll S, Moran J, Smoller JW, Chambert K, Belliveau RA. Mol Psychiatry. 2015 Oct 27
  • Manic episodes are related to changes in frontal cortex: a longitudinal neuroimaging study of bipolar disorder 1. Abé C, Ekman CJ, Sellgren C, Petrovic P, Ingvar M, Landén M.Brain. 2015 Dec 7;41(1):150093.
  • Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. Li M, Luo XJ, Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S, Mühleisen TW, Degenhardt FA, Nöthen MM, Schulze TG, Grigoroiu-Serbanescu M, Li H, Fuller CK, Chen C, Dong Q, Chen C, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Preisig M, Kutalik Z, Castelao E, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG; MooDS Consortium; Swedish Bipolar Study Group, Rietschel M, Liu C, Kleinman JE, Hyde TM, Weinberger DR, Su B.Br J Psychiatry. 2015 Sep 3.
  • CSF neuroinflammatory biomarkers in bipolar disorder are associated with cognitive impairment.Rolstad S, Jakobsson J, Sellgren C, Isgren A, Ekman CJ, Bjerke M, Blennow K, Zetterberg H, Pålsson E, Landén M. Eur Neuropsychopharmacol. 2015 Aug;25(8):1091-8.
  • Monocyte and microglial activation in patients with mood-stabilized bipolar disorder.Jakobsson J, Bjerke M, Sahebi S, Isgren A, Ekman CJ, Sellgren C, Olsson B, Zetterberg H, Blennow K, Pålsson E, Landén M.J Psychiatry Neurosci. 2015 Jul;40(4):250-8.
  • Cognitive performance and cerebrospinal fluid biomarkers of neurodegeneration: a study of patients with bipolar disorder and healthy controls. Rolstad S, Jakobsson J, Sellgren C, Ekman CJ, Blennow K, Zetterberg H, Pålsson E, Landén M. PLoS One. 2015 May 8;10(5).
  • Gender differences in the treatment of patients with bipolar disorder: a study of 7354 patients. Karanti A, Bobeck C, Osterman M, Kardell M, Tidemalm D, Runeson B, Lichtenstein P, Landén M. J Affect Disord. 2015 Mar 15;174:303-9.
  • Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population. Song J, Bergen SE, Kuja-Halkola R, Larsson H, Landén M, Lichtenstein P. Bipolar Disord. 2015 Mar;17(2):184-93.
  • Bipolar disorder and leadership–a total population study. Kyaga S, Lichtenstein P, Boman M, Landén M. Acta Psychiatr Scand. 2015 Feb;131(2):111-9.
  • Markers of glutamate signaling in cerebrospinal fluid and serum from patients with bipolar disorder and healthy controls. Pålsson E, Jakobsson J, Södersten K, Fujita Y, Sellgren C, Ekman CJ, Ågren H, Hashimoto K, Landén M. Eur Neuropsychopharmacol. 2015 Jan;25(1):133-40.
  • Cognitive functioning in clinically stable patients with bipolar disorder I and II. Sparding T, Silander K, Pålsson E, Östlind J, Sellgren C, Ekman CJ, Joas E, Hansen S, Landén M. PLoS One. 2015 Jan 23;10(1):e0115562.
  • Increased cerebrospinal fluid interleukin-8 in bipolar disorder patients associated with lithium and antipsychotic treatment. Isgren A, Jakobsson J, Pålsson E, Ekman CJ, Johansson AG, Sellgren C, Blennow K, Zetterberg H, Landén M. Brain Behav Immun. 2015 Jan;43:198-204.

2014

  • Förändringar i förskrivningen till patienter med bipolära syndrom – Ökad användning av lamotrigin och minskning av litium. Karanti A, Kardell M, Lundberg U, Landen M. Lakartidningen. 2014 Dec 16;111(51-52).
  • Low neuropeptide Y in cerebrospinal fluid in bipolar patients is associated with previous and prospective suicide attempts. Sandberg JV, Jakobsson J, Pålsson E, Landén M, Mathé AA. Eur Neuropsychopharmacol. 2014 Dec;24(12):1907-15.
  • The risk of switch to mania in patients with bipolar disorder during treatment with an antidepressant alone and in combination with a mood stabilizer. Viktorin A, Lichtenstein P, Thase ME, Larsson H, Lundholm C, Magnusson PK, Landén M. Am J Psychiatry. 2014 Oct;171(10):1067-73.
  • Subcortical morphometry and psychomotor function in euthymic bipolar disorder with a history of psychosis. Liberg B, Ekman CJ, Sellgren C, Johansson AG, Landén M. Brain Imaging Behav. 2014 Jul 18.
  • Blood-cerebrospinal fluid barrier dysfunction in patients with bipolar disorder in relation to antipsychotic treatment. Zetterberg H, Jakobsson J, Redsäter M, Andreasson U, Pålsson E, Ekman CJ, Sellgren C, Johansson AG, Blennow K, Landén M. Psychiatry Res. 2014 Apr 5.
  • The Association Between Schizophrenia and Rheumatoid Arthritis: A Nationwide Population-Based Swedish Study on Intraindividual and Familial Risks.Sellgren C, Frisell T, Lichtenstein P, Landèn M, Askling J. Schizophr Bull. 2014 Apr 8.
  • Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: A study of two independent cohorts. Södersten K, Pålsson E, Ishima T, Funa K, Landén M, Kenji Hashimoto, Agren H. J Affect Disord. 2014 May;160:1-9.
  • Attempted suicide in bipolar disorder: risk factors in a cohort of 6086 patients. Tidemalm D, Haglund A, Karanti A, Landén M, Runeson B. PLoS One. 2014 Apr 4;9(4).
  • Elevated Concentrations of Neurofilament Light Chain in the Cerebrospinal Fluid of Bipolar Disorder Patients. Jakobsson J, Bjerke M, Ekman CJ, Sellgren C, Johansson AG, Zetterberg H, Blennow K, Landén M. Neuropsychopharmacology. 2014 Apr 3.
  • Vertex-based morphometry in euthymic bipolar disorder implicates striatal regions involved in psychomotor function. Liberg B, Ekman CJ, Sellgren C, Johansson A, Landén M. Psychiatry Res. 2014 Mar 30;221(3):173-8.
  • The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Thompson PM et al. Brain Imaging Behav. 2014 Jun;8(2):153-82.

2013

  • Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. Ruderfer DM, Fanous AH, Ripke S, McQuillin A, Amdur RL; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium; Cross-Disorder Working Group of the Psychiatric Genomics Consortium, Gejman PV, O’Donovan MC, Andreassen OA, Djurovic S, Hultman CM, Kelsoe JR, Jamain S, Landén M, Leboyer M, Nimgaonkar V, Nurnberger J, Smoller JW, Craddock N, Corvin A, Sullivan PF, Holmans P, Sklar P, Kendler KS. Mol Psychiatry. 2013 Nov 26.
  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Cross-Disorder Group of the Psychiatric Genomics Consortium. Nat Genet. 2013 Sep;45(9):984-94.
  • Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes. Hukic DS, Frisén L, Backlund L, Lavebratt C, Landén M, Träskman-Bendz L, Edman G, Schalling M, Ösby U. PLoS One. 2013 Jul 5;8(7)
  • The societal cost of bipolar disorder in Sweden. Ekman M, Granström O, Omérov S, Jacob J, Landén M. Soc Psychiatry Psychiatr Epidemiol. 2013 Oct;48(10):1601-10.
  • Risk of bipolar disorder and schizophrenia in relatives of people with attention-deficit hyperactivity disorder. Larsson H, Rydén E, Boman M, Långström N, Lichtenstein P, Landén M. Br J Psychiatry. 2013 Aug;203(2):103-6. Jakobsson J, Stridsberg M, Zetterberg H, Blennow K, Ekman CJ, Johansson AG, Sellgren C, Landén M. Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder. J Psychiatry Neurosci. 2013 Jul;38(4):E21-6.
  • Pålsson E, Figueras C, Johansson AG, Ekman CJ, Hultman B, Ostlind J, Landén M. Neurocognitive function in bipolar disorder: a comparison between bipolar I and II disorder and matched controls. BMC Psychiatry. 2013 Jun 7;13:165.
  • Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Vasquez AA, Hibar DP, Franke B, Martin NG, Wright MJ. Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Mol Psychiatry. 2013 May 14.
  • Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O’Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium, Schork NJ, Andreassen OA, Dale AM. All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs. PLoS Genet. 2013 Apr;9(4):e1003449.
  • Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, Kendler K, Lee PH, Neale BM, Nurnberger JI, Ripke S, Santangelo S, Sullivan PF. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013 Apr 20;381(9875):1371-9.
  • Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M. The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression. Mol Psychiatry. 2013 Mar 5.
  • Jakobsson J, Zetterberg H, Blennow K, Ekman CJ, Johansson AG, Landén M. Altered concentrations of amyloid precursor protein metabolites in the cerebrospinal fluid of patients with bipolar disorder. Neuropsychopharmacology. 2013 Mar;38(4):664-72.

2012

  • Lundberg J, Tiger M, Landén M, Halldin C, Farde L. Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder. Int J Neuropsychopharmacol. 2012 Jan 16:1-6.
  • Johansson AGM, Nikamo P, Schalling M, Landén M. Polymorphisms in AKR1C4 and HSD3B2 and differences in serum DHEAS and progesterone are associated with paranoid ideation during mania or hypomania in bipolar disorder. Eur Neuropsychopharmacol. 2012 Sep;22(9):632-40.
  • Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium A Mega-Analysis of Genome-Wide Association Studies for Major Depressive Disorder. Mol Psychiatry. 2012 Apr 3. doi: 10.1038/mp.2012.21.
  • Bergmann O, Liebl J, Bernard S, Alkass K, Yeung MS, Steier P, Kutschera W, Johnson L, Landén M, Druid H, Spalding KL, Frisén J. The age of olfactory bulb neurons in humans. Neuron. 2012 May 24;74(4):634-9.
  • Selvaggi G, Dhejne C, Landén M and Elander E. The 2011 WPATH Standards of Care and penile reconstruction in female-to-male transsexual individuals. Adv Urol. 2012;2012:581712.
  • Bergen SE, O’Dushlaine CT, Ripke S, Lee PH, Ruderfer DM, Akterin S, Moran JL, Chambert KD, Handsaker RE, Backlund L, Osby U, McCarroll S, Landen M, Scolnick EM, Magnusson PK, Lichtenstein P, Hultman CM, Purcell SM, Sklar P, Sullivan PF. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry. 2012 Sep;17(9):880-6. doi: 10.1038/mp.2012.73.
  • Anne C Zachau, AC, Landén M, Mobarrez F, Nybom R, Wallén H, Wetterberg L Leukocyte-derived microparticles and scanning electron microscopic structures in two fractions of fresh cerebrospinal fluid in amyotrophic lateral sclerosis: a case reportJournal of Medical Case Reports 2012, 6:274 doi:10.1186/1752-1947-6-274
  • Backlund L, Lavebratt C, Frisén L, Nikamo P, Hukic Sudic D, Träskman-Bendz L, Landén M, Edman G, Vawter M P, Ösby U, Schalling M. P2RX7: Expression Responds to Sleep Deprivation and Associates with Rapid Cycling in Bipolar Disorder Type 1. PLoS One. 2012;7(8):e43057.
  • Olsson SK, Sellgren C, Engberg G, Landén M, Erhardt S. Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder. Bipolar Disord. 2012 Nov;14(7):719-26. doi: 10.1111/bdi.12009.
  • Johansson V, Nybom R, Wetterberg L, Hultman CM, Cannon TD, Johansson AGM, Ekman CJ, and Landén M. Microscopic particles in two fractions of fresh cerebrospinal fluid in twins with schizophrenia or bipolar disorder and in healthy controls. PLoS One. 2012;7(9):e45994. doi: 10.1371/journal.pone.0045994
  • Bäck A, Andersson Sundell K, Horne R, Landén M, Mårdby A-C. The Medication Adherence Report Scale (MARS-5) in a Swedish sample with bipolar disorder – a pilot study. Int J Pers Cent Med. 2012: June: 2: 2.
  • Kyaga S, Landén M, Boman M, Hultman CM, Långström N, Lichtenstein P. Mental illness, suicide and creativity: 40-Year prospective total population study. J Psychiatr Res. 2012 Oct 9. pii: S0022-3956(12)00280-4. doi: 10.1016/j.jpsychires.2012.09.010.
  • Power RA, Kyaga S, Uher, R, MacCabe JH, Långström N, Landén M, McGuffin P, Lewis CM, Lichtenstein P, and Svensson AC (2012) Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa or substance abuse and their unaffected siblings. Arch Gen Psychiatry. 2012 Nov 12:1-8. doi: 10.1001/jamapsychiatry.2013.268.
  • Lundh A, Forsman M, Serlachius E, Lichtenstein P, Landén M. Outcomes of child psychiatric treatment. Acta Psychiatr Scand. 2012 Nov 22. doi: 10.1111/acps.12043.
  • Mobarrez F, Nybom R, Johansson V, Hultman CM, Wallén H, Landén M, Wetterberg L. Microparticles and microscopic structures in three fractions of fresh cerebrospinal fluid in schizophrenia: case report of twins, Schizophr Res. 2012 Nov 19. doi:pii: S0920-9964(12)00604-4. 10.1016/j.schres.2012.10.030.

2011

  • Söderlund J, Olsson SK, Samuelsson M, Walther-Jallow L, Erhardt S, Landén M, Engberg G. Elevation of cerebrospinal fluid interleukin-1ß in bipolar disorder. Journal of Psychiatry and Neuroscience. 2011(36):114-8. doi: 10.1503/jpn.100080.
  • Månsson M, Norström K, Holte J, Landin-Wilhelmsen K, Dahlgren E, Landén M. Sexuality and Psychological Wellbeing in Women with Polycystic Ovary Compared with Healthy Controls. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2011. doi:10.1016/j.ejogrb.2010.12.012
  • Dhejne C, Långström N, Lichtenstein P, Boman M, Johansson ALV, Landén M. Long-term follow-up of transsexual persons undergoing sex reassignment surgery: cohort study in Sweden. PLoS One. 2011 Feb 22;6(2):e16885
  • Kyaga S, Lichtenstein P, Boman M, Långström N, Hultman CH, Landén M. Creativity and mental disorder: family study of 300 000 people with severe mental disorder. Br J Psychiatry. 2011 Nov;199:373-9.
  • Jedel E, Gustafson D, Waern M, Sverrisdottir YB, Landén M, Janson PO, Labrie F, Ohlsson C, Stener-Victorin E. Sex steroids, insulin sensitivity and sympathetic nerve activity in relation to affective symptoms in women with polycystic ovary syndrome. Psychoneuroendocrinology. 2011 May 5.
  • Johansson AGM, Nikamo P, Schalling M, Landén M. AKR1C4 gene variant associated with low euthymic serum progesterone and a history of mood irritability in males with bipolar disorder. J Affect Disord. 2011 Sep;133(1-2):346-51.
  • Lundh A, Kowalski J, Sundberg CJ, Landén M. A comparison of seminar and computer based training on the accuracy and reliability of raters using the Children’s Global Assessment Scale (CGAS) Adm Policy Ment Health. 2011 Jul 22 doi: 10.1007/s10488-011-0369-5
  • Sellgren C, Landén M, Lichtenstein P, Hultman CM, Långström N. Validity of bipolar disorder hospital discharge diagnoses: file review and multiple register linkage in Sweden. Acta Psychiatr Scand. 2011 Aug 13. doi: 10.1111/j.1600-0447.2011.01747.
  • Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nature Genetics. 2011 Sep 18;43(10):977-83. doi: 10.1038/ng.943
  • Eriksson O, Landén M, Sundblad C, Holte J, Eriksson E, Naessén T. Ovarian morphology in premenstrual dysphoria. Psychoneuroendocrinology. 2011 Oct 3
  • Backlund L, Nikamo P, Hukic DS, Ek IR, Träskman-Bendz L, Landén M, Edman G, Schalling M, Frisén L, Osby U. Cognitive manic symptoms associated with the P2RX7 gene in bipolar disorder. Bipolar Disord. 2011 Aug-Sep;13(5-6):500-8. doi: 10.1111/j.1399-5618.2011.00952.

2010

  • Jedel E, Waern M, Gustafson D, Landén M, Eriksson E, Holm G, Nilsson L, Lind AK, Janson PO, Stener-Victorin E. Anxiety and depression symptoms in women with polycystic ovary syndrome compared with controls matched for body mass index. 2010; Hum Reprod:25:450-6.
  • Olsson SK, Samuelsson M, Erhardt S, Engberg G, Nordin C, Landén M. Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder. Journal of Psychiatry and Neurosci. 2010 May;35(3):195-9.
  • Båve U, Landén M, Nybom R, Wetterberg L: Morphology of structures by scanning electron microscope (SEM) in early fractions of cerebrospinal fluid (CSF) in 59 patients with bipolar disorder. Bipolar Disorders. 2010 May;12(3):298-305.
  • Lundh A, Kowalski J, Sundberg C-J, Gumpert C, Landén M. Children’s Global Assessment Scale (CGAS) in a naturalistic clinical setting: inter-rater reliability and comparison with expert ratings. Psychiatry Res. 2010 May 15;177(1-2):206-210.
  • Jonsson L, Ljunggren E, Bremer A, Pedersen C, Landén M, Kent Thuresson, Giacobini M, and Melke J. Mutation screening of melatonin-related genes in patients with autism spectrum disorders. BMC Medical Genomics. 2010; Apr 8;3:10.
  • Ekman CJ, Lind J, Ingvar M, Rydén E, Landén M. Manic episodes are associated with grey matter volume reduction – a voxel-based morphometry brain analysis. Acta Psych Scand. 2010 Dec;122(6):507-15

2009

  • Landén M, Erlandsson H, Bengtsson F, Andersch B, Eriksson E. Short onset of action of a serotonin reuptake inhibitor when used to reduce premenstrual irritability. Neuropsychopharmacology, 2009; 34(3):585-92.
  • Henningsson S, Jonsson L, Ljunggren E, Westberg L, Gillberg C, Råstam M, Anckarsäter, H., Nygren, G., Landén M, Thuresson K, Betancur C, Leboyer M, Eriksson E, Melke J. Possible association between the androgen receptor gene and autism spectrum disorder. Psychoneuroendocrinology. 2009 Jan 22.
  • Rydén E, Thase ME, Stråht D, Åberg-Wistedt A, Bejerot S, Landén M. A history of childhood attention-deficit hyperactivity disorder (ADHD) impacts clinical outcome in adult bipolar patients regardless of current ADHD. Acta Psych Scand. 2009;120(3):239-46.
  • Westberg L, Henningsson S, Landén M, Annerbrink K, Melke J, Nilsson S, Rosmond R, Holm G, Anckarsäter H, Eriksson E, Influence of androgen receptor repeat polymorphisms on personality traits in men. J Psychiatry Neurosci 2009; 34:205-213.
  • Rydén E, Johansson C, Blennow K, Landén M. Lower CSF HVA and 5-HIAA in bipolar disorder type 1 with a history of childhood ADHD. Journal of Neural Transmission. 2009;116:1667-74